Directions for itching of skin irritation, inflammation, and rashes: - adults and children 2 years and older: apply sparingly to affected area, not more than 3 to 4 times daily. - children under 2 years: ask a doctor for external anal and genital itching, adults: - Gently cleanse, rinse thoroughly, and dry the affected area prior to application. - apply to affected area not more than 3 to 4 times daily. - children under 12 years: ask a doctor